Frequent Questions

For SW-846 Method 5030 combined with Method 8260, is the Tune Batch equal to the Analytical Batch?

For method 5030 combined with method 8260, is the Tune Batch equal to the Analytical Batch, i.e., does all of the associated QC analyzed within a Tune Batch equal that which should be included in the Analytical Batch (method blank, laboratory control sample, matrix spike/matrix spike duplicate)?


In the following example, analysis batch is interpreted as being within a tune window, which would make the analytical batch equivalent to the tune:

Analysis batch – A group of up to 20 samples, sample extracts, or sample digestates (including QC aliquots), that are analyzed together on the same instrument. For the analysis of volatiles, there may be no sample preparation equipment other than that attached directly to the determinative instrument (e.g., Methods 5030B and 8260B), so the analysis batch drives the frequency of the method blank and LCS for volatiles, as well as the frequency of calibration verification standards for methods using external standard calibration. The limit of 20 in the analysis batch includes all the analyses, including the method blank, LCS, MS, and MSD, so that an analysis batch for volatiles will include fewer than 20 field samples.

The statement that an analysis batch will have <20 field samples implies that the entire batch must fit within the tune window.

In the end it comes down to how a regulating body, site QAPP, or QA/QC program defines analysis batch. Most labs seem to tend toward the tune window being the equivalent of the analysis batch to avoid problems with auditors and comply with as many programs as possible.

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